March 4, 2008

PUBLICATIONS

 

JOURNALS

27. M. Shahrooz Amin, YoungKeun Park, Niyom Lue, Ramachandra R. Dasari, Kamran Badizadegan, Michael S. Feld, and Gabriel Popescu, “Microrheology of red blood cell membranes using dynamic scattering microscopy”, Optics Express, 15, 17001 (2007).

26. N. Lue, J. Bewersdorf, M. D. Lessard, K. Badizadegan, R. R. Dasari, M. S. Feld, and G. Popescu, “Tissue refractometry using Hilbert phase microscopy”, Opt. Lett., 32, 522 (2007).

25. G. Popescu, Y. K. Park, R. R. Dasari, K. Badizadegan, and M. S. Feld, “Coherence properties of red blood cell membrane motions”, Phys. Rev. E, 76, 021902 (2007).

24. Y. K. Park, G. Popescu, R. R. Dasari, K. Badizadegan and M. S. Feld, “Fresnel particle tracking in three dimensions using diffraction phase microscopy”, Opt. Lett., 32, 811 (2007).

23. N. Lue, W. Choi, G. Popescu, T. Ikeda, R. R. Dasari, K. Badizadegan, and M. S. Feld, “Quantitative phase imaging of live cells using fast Fourier phase microscopy”, Appl. Opt. 32, 811 (2007)

22. G. Popescu, T. Ikeda, K. Goda, C. A. Best-Popescu, M. L. Laposata, S. Manley, R. R. Dasari, K. Badizadegan, and M. S. Feld, “Optical measurement of cell membrane tension”, Phys. Rev. Lett., 97, 218101 (2006).

21. M. Hunter, V. Backman, G. Popescu, M. Kalashnikov, C. W. Boone, A. Wax, G. Venkatesh, K. Badizadegan, G. D. Stoner and M. S. Feld, "Tissue Self-Affinity and Light Scattering in the Born Approximation: A New Model for Precancer Diagnosis", Phys. Rev. Lett. 97, 138102 (2006).

20. Y. K. Park, G. Popescu, K. Badizadegan, R. R. Dasari and M. S. Feld, "Diffraction phase and fluorescence microscopy", Opt. Exp. 14, 8263, (2006).

19. N. Lue, G. Popescu, R. R. Dasari, K. Badizadegan, M. S. Feld, “Live cell refractometry using microfluidic devices”, Opt. Lett., 31, 2579 (2006).

18. G. Popescu, K. Badizadegan, R. R. Dasari, M. S. Feld, “Observation of dynamic subdomains in red blood cells”, J. Biomed. Opt. Lett., 11, 040503 (2006).

17. G. Popescu, T. Ikeda, R. R. Dasari, and M. S. Feld, “Diffraction phase microscopy for quantifying cell structure and dynamics”, Opt. Lett., 31, 775 (2006).

16. G. Popescu and A. Dogariu, “Scattering of low coherence radiation and applications”, Eur. J. Phys., review article, 32, 73 (2005).

15. G. Popescu, T. Ikeda, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Erythrocyte structure and dynamics quantified by Hilbert phase microscopy”, J. Biomed. Optics Lett., 10, 060503 (2005).

14. T. Ikeda, G. Popescu, R. R. Dasari, and M. S. Feld, “Hilbert phase microscopy for investigating fast dynamics in transparent systems”, Opt. Lett., 30, 1165 (2005).

13. A. Ahn, C. Yang, A. Wax, G. Popescu, et al., “Harmonic phase dispersion microscope with a Mach-Zender interferometer”, Appl. Opt., 44, 1188 (2005).

12. G. Popescu, L. P. Deflores, K. Badizadegan, et al., “Fourier phase microscopy for investigation of biological structure and dynamics”, 29, 2503 Opt. Lett. (2004).

11. H. Iwai, C. Fang-Yen, G. Popescu, et al., “Quantitative phase imaging using actively stabilized phase shifting low-coherence interferometry”, 29, 2399, Opt. Lett. (2004).

10. A. Dogariu and G. Popescu, “High-resolution spatial and spectral characterization of optical fields”, OPN, vol. 13, No. 12, 21 (2002).

9. A. Dogariu and G. Popescu, “Measuring the phase of spatially coherent polychromatic fields”, Phys. Rev. Lett., vol. 89, 243902 (2002).

8. G. Popescu and A. Dogariu, “Spectral anomalies at wavefront dislocations”, Phys. Rev. Lett., vol. 85, 183902, (2002).

7. G. Popescu, A Dogariu, and R. Rajagopolan, “Spatially resolved microrheology using localized coherence volumes”, Phys. Rev. E, vol. 65, 041504 (2002).

6. G. Popescu and A. Dogariu, “Dynamic light scattering in sub-diffusive regimes”, Appl. Optics, vol. 40, 4215 (2001).

5. G. Popescu and A. Dogariu, “Dynamic light scattering in localized coherence volumes”, Opt. Lett., vol. 26, 551 (2001).

4. G. Popescu and A. Dogariu, “Ballistic attenuation of low-coherence fields” Appl. Optics, vol. 39, 4469, (2000).

3. G. Popescu, C. Mujat, and A. Dogariu, “Evidence of scattering anisotropy effects on boundary conditions of the diffusion equation”, Phys. Rev. E, vol. 61, 4523, (2000).

2. G. Popescu and A. Dogariu, “Optical path-length spectroscopy of wave propagation in random media”, Opt. Lett.. vol. 24, 442, (1999).

1. M. L. Pascu, B. Carstocea, G. Popescu, et al, “Imaging corneal cells using low power laser beams”, Lasers in Medical Science, 13, 148, (1998).

 

LECTURES/ INVITED TALKS

*  “Quantitative phase imaging: watching cells dance”, Bioengineering Graduate Seminar, UIUC, February 2008

*  “Nanoscale dynamics of live cells quantified by optical interferometry”, DSP Seminar, Beckman Institute, UIUC, January 2008

*  “Coherence properties of cell membrane motions”, Photonics West, San Jose, CA, January 2008.

*  “Nanoscale fluctuations of live cell membranes quantified by optical interferometry”, Physics Colloquium, University of Delaware, November 2007

*  “Optical measurement of cell membrane dynamics: taking the pulse of red blood cells”, BioInterest Group Seminar Series, UIUC, October 2007

*  “Fluctuations of red blood cells quantified by optical interferometry”, Optical Microsystems Conference, Capri, Italy, October 2007

*  “Nanoscale fluctuations of live cell membranes quantified by optical interferometry”, Nanohour Talk, Beckman Institute, UIUC, September 2007

*  “Nanoscale structure and dynamics of live cells measured by quantitative phase imaging”, Frontiers In Microscopy II Conference, The Jackson Laboratory, Bar Harbor, Maine, June 2007

*  “Nanoscale imaging of live cells quantified by optical interferometry”, Physics Seminar Series, University of Massachusetts at Boston, June 2007

*  “Quantitative phase imaging: watching cells waltz”, Modern optics and spectroscopy seminar at MIT, October 2006.

*  “Nanoscale investigations of live cells using optical interferometry”, invited talk, The Gordon Conference, Lasers in Medicine and biology, Holderness, NH, July 2006

*  “Quantitative phase microscopy: watching red blood cells dance”, invited talk, Engineering Foundation Conference, Copper Mountain, Colorado, July 2005.

*  "Quantifying red blood cell nanoscale fluctuations using Hilbert phase microscopy", Physics Department seminar, University of Massachusetts at Lowell, Lowell, MA, September 2005.

*   “Quantifying the structure and dynamics of live cells using quantitative phase microscopy”, Biomedical Engineering Department seminar, Tufts University, Medford, MA, November 2004.

*  “Structure and dynamics of live cells quantified by Fourier Phase Microscopy”, Physics Department Seminar, Clark University, Worcester, MA, November 2004.

*   “Nanoscale microscopy of living cells using optical interferometry”, OSA Student chapter seminar series, MIT, May 12, 2006.

*  “Quantitative phase imaging of live cells”, Laser Interferometer Gravitational-Wave Observatory (LIGO) seminar, MIT, Cambridge, MA, May 2005.

 

PRESS RELEASE/ HIGHLIGHTS

  • “Watching the insides of a cell”, in Technology review, November 15, 2006 (online)
  •  “Imaging cells on the move”, in Biophotonics International, November 2006
  • “MIT Technique Reveals Inner Lives of Red Blood Cells”, in MIT Tech Talk newspaper, October 16, 2006 (online)
  •  “Unlocking a Cell’s Inner Secrets”, R&D Magazine, February, 2007 (online)
  • “Unique partnerships move Spectroscopy from lab to clinic”, NCRR Reporter, 9, Winter 2007 (online)

 

 

CONFERENCES

44. Gabriel Popescu, YoungKeun Park, Niyom Lue, Catherine Best-Popescu, Ramachandra R. Dasari, Kamran Badizadegan, and Michael S. Feld, “Optical imaging of cell mass and growth dynamics”, Photonics West, San Jose, CA, January 2008.

43. Gabriel Popescu, M. Shahrooz Amin, YongKeun Park, Niyom Lue, Ramachandra R. Dasari, Kamran Badizadegan, and Michael S. Feld, “Dynamic scattering microscopy”, Photonics West, San Jose, CA, January 2008.

42. Gabriel Popescu, Niyom Lue, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld, “Refractive index of cells and tissues measured by quantitative phase imaging” Photonics West, San Jose, CA, January 2008.

41. Gabriel Popescu, YoungKeun Park, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld, “Coherence properties of cell membrane motions”, Photonics West, San Jose, CA, January 2008.

40. Gabriel Popescu, YongKeun Park, Niyom Lue, Kamran Badizadegan, Ramachandra R. Dasari and Michael S. Feld, “Nanoscale structure and dynamics of live cells measured by quantitative phase imaging”, Microscopy II Conference, Bar Harbor, Maine, June 18-21, 2007

39. Gabriel Popescu, Niyom Lue, YongKeun Park, Kamran Badizadegan, Ramachandra R. Dasari and Michael S. Feld, “Quantitative phase imaging of cells and tissues”, Optical Microsystems Conference, Capri, Italy, October 2007.

39. Gabriel Popescu, YongKeun Park, Kamran Badizadegan, Ramachandra R. Dasari and Michael S. Feld, “Fluctuations of red blood cells quantified by optical interferometry”, Optical Microsystems Conference, Capri, Italy, October 2007.

38. YongKeun Park, Gabriel Popescu, Catherine Best-Popescu, Kamran Badizadegan, Ramachandra R. Dasari and Michael S. Feld, “Optical measurements of cell membrane rheology”, Engineering Foundation Conference, Naples, FL, June 14-14, 2007.

37. Niyom Lue, Wonshik Choi, Gabriel Popescu, Ramachandra R. Dasari, Kamran Badizadegan, and Michael S. Feld, “Confocal diffraction phase microscopy”, Engineering Foundation Conference, Naples, FL, June 14-14, 2007.

36. Gabriel Popescu, Niyom Lue, YoungKeun Park, Kamran Badizadegan, Ramachandra. R. Dasari, Michael. S. Feld, “Quantitative phase imaging of eukaryotic cells”, Engineering Foundation Conference, Naples, FL, June 14-14, 2007.

35. Y. K. Park, G. Popescu, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Diffraction phase microscopy”, Photonics West, San Jose, CA, 20-25 January, 2007.

34. N. Lue, G. Popescu, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Live cell refractometry using quantitative phase imaging”, Photonics West, San Jose, CA, 20-25 January, 2007.

33. G. Popescu, Y. K. Park, Catherine A. Best-Popescu, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Red blood cell fluctuations during osmolarity changes”, OSA Annual meeting, Rochester, NY, Oct. 8-12, 2006.

32. G. Popescu, N. Lue, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Live cell refractometry using microfluidic devices”, OSA Annual meeting, Rochester, NY, Oct. 8-12, 2006.

31. G. Popescu, Y. K. Park, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Diffraction phase and fluorescence microscopy”, OSA Annual meeting, Rochester, NY, Oct. 8-12, 2006.

30. G. Popescu, Y. K. Park, N. Lue, S. Amin, T. Ikeda, K. Badizadegan, R. Dasari, M. S. Feld, “Nanoscale microscopy of living cells using optical interferometry”, The Gordon Conference, Lasers in Medicine and biology, Holderness, NH, July 2006.

29. N. Lue, W. Choi, G. Popescu, T. Ikeda, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Quantitative phase imaging of living cell using fast Fourier phase microscopy”, The Gordon Conference, Lasers in Medicine and biology, Holderness, NH, July 2006.

28. Y. K. Park, G, Popescu, T. Ikeda, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Diffraction phase microscopy for quantifying structures and dynamics of live cells”, The Gordon Conference, Lasers in Medicine and biology, Holderness, NH, July 2006.

27. G. Popescu, T. Ikeda, C. A. Best, K. Goda, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Observation of red blood cell tension using actively stabilized Hilbert phase microscopy”, Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-22, 2006.

26. Y. Park, G. Popescu, T. Ikeda, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Diffraction phase microscopy”, Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-22, 2006.

25. N. Lue, G. Popescu, T. Ikeda, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Live cell refractometry using Hilbert phase microscopy”, Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-22, 2006.

24. M. S. Amin, G. Popescu, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Dynamic light microscopy for probing cell rheology”, Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-22, 2006.

23. G. Popescu, T. Ikeda, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Quantitative phase microscopy: watching red blood cells dance”, invited paper, Engineering Foundation Conference, Copper Mountain, Colorado, July 24-28, 2005.

22. G. Popescu, T. Ikeda, K. Badizadegan, R. R. Dasari, and M. S. Feld, “Nanoscale investigation of live cells using quantitative phase microscopy”, Engineering Foundation Conference, Copper Mountain, Colorado, July 24-28, 2005.

21. G. Popescu, T Ikeda, K. Badizadegan, R. R. Dasari and M. S. Feld, “Nanometer fluctuations of erythrocytes imaged by Hilbert phase microscopy”, European Conference of Biomedical Optics, Munich, Germany, June 12-16, 2005 (SPIE 5864-0A).

20. G. Popescu, K. Badizadegan, R. R. Dasari and M. S. Feld, “Motility of live cancer cells quantified by Fourier phase microscopy”, European Conference of Biomedical Optics, Munich, Germany, June 12-16, 2005 (SPIE 5864-0B).

19. G. Popescu, K. Badizadegan, R. R. Dasari and M. S. Feld, “Imaging erythrocyte dynamic subdomains by Fourier phase microscopy”, ASIP Meeting of Experimental Biology, San Diego, April 2-6, 2005.

18. G. Popescu, L. Deflores, K. Badizadegan, et al., “Investigation of live cells using common-path low-coherence phase microscopy”, OSA Annual meeting, Rochester, NY, Oct. 10-14, 2004.

17. G. Popescu, L. Deflores, K. Badizadegan, et al., “Phase reconstruction of two-dimensional polychromatic fields”, OSA Annual meeting, Rochester, NY, Oct. 10-14, 2004.

16. G. Popescu, L. Deflores, K. Badizadegan, et al., “Nanometer investigation of live cells using Fourier phase microscopy”, The Gordon conference, Lasers in Medicine and Biology, Meriden, NH, 2004.

15. G. Popescu, C. Fang-Yen, L. P. Deflores, et al. “Seeing small biological structures with light”, ICOLS, 2003.

14. G. Popescu, and A. Dogariu, “Spectral behavior at wavefront dislocations”, OSA Annual meeting, Orlando, Fl, Sept. 29-Oct. 4, 2002.

13. G. Popescu, J. Biggerstaff, and A. Dogariu, “Optical rheology of blood”, OSA Annual meeting, Orlando, Fl, Sept. 29-Oct. 4, 2002.

12. G. Popescu, J. Biggerstaff, S. Patel, and A. Dogariu, “Optical microrheology in localized coherence volumes”, Postdeadline paper, OSA Annual Meeting, Long Beach, Ca, Oct. 14-18, 2001.

11. G. Popescu and A. Dogariu, “Dynamic light scattering with low-coherence fields”, OSA Annual meeting, Providence, RI, Oct. 22-26, 2000.

10. G. Popescu and A. Dogariu, “Dynamic multiple light scattering in sub-diffusive regimes”, OSA Topical Meeting, Photon Correlation and Scattering, August 21-23, Whistler, BC, Canada, 2000.

9. G. Popescu and A. Dogariu, “Investigation of particulate systems using optical path-length spectroscopy”, MRS Spring Meeting, San Francisco, April 24-28, 2000.

8. G. Popescu, W. G. Easter, and A. Dogariu, “Study of the sedimentation process using optical path-length spectroscopy”, MRS Spring Meeting, San Francisco, April 24-28, 2000.

7. G. Popescu, A. Dogariu, “Optical characterization of volume-scattering backgrounds”, SPIE 14th Annual International Symposium on Aerosense, Orlando, 24-28 April, 2000.

6. G. Popescu, C. Mujat, and A Dogariu, “Optical path-length spectroscopy of multiple-scattering media”, OSA Annual meeting, Santa Clara, Sept. 26-Oct. 1, 1999.

5. G. Popescu, M. Lauwidjaja, L. Denney, A. Dogariu, and K. Richardson, “Aging effects in CMP slurries probed by multiple light scattering”, The 193rd Meeting of Electrochemical Society, San Diego, May 3-8, 1998.

4. M. Lauwidjaja, G. Popescu, L. Denney, A. Dogariu, and K. Richardson, “Chemical and structural characterization of aluminum oxide slurries”, The 193rd Meeting of Electrochemical Society, May 3-8, 1998.

3. M. L. Pascu, B. Carstocea, G. Popescu, “New laser method to characterize rabbit eye cornea”, 5th Int. Congress of the European Medical Laser Association, Florence, 1997

2. M.L.Pascu, B. Carstocea, G. Popescu, L. Gafencu, S. Apostol, N. Moise, M. Roman, C.M. Ticos “Laser method for corneal structure investigation”, Proc. of ROMOPTO '97, SPIE vol. 3405, part two, p. 665-672, Bucharest, 1997.

1. B. Carstocea, O. Gafencu, S. Apostol, M. Ionita, M.L.Pascu, G. Popescu, M. Roman, S. Hogiu, “Preliminary studies of rabbit corneal structure using laser beams”, SPIE vol.2930, p.50-57, Lasers in Ophthalmology IV, BIOS'96,  Viena, 1996.